Hypopyon is a medical condition involving inflammatory cells in the anterior chamber of the eye. It is an exudate rich in white blood cells, seen in the anterior chamber, usually accompanied by redness of the conjunctiva and the underlying episclera.
If we suspect an ocular condition or disease,
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diagnostic tests to determined our next steps.
Hypopyon can be present in a corneal ulcer. Behçet's disease, endophthalmitis, panuveitis/panophthalmitis, and adverse reactions to some drugs (such as rifabutin).
Hypopyon is also known as sterile pus, as it occurs due to the release of toxins and not by the actual invasion of pathogens. The toxins secreted by the pathogens mediate the outpouring of leukocytes that settle in the anterior chamber of the eye.
A hypopyon should not be drained, because it offers protection against the invading pathogen due to the presence of white blood cells, although long-standing hypopyon can cause close-angle glaucoma and anterior synechiae.
Intravitreal antibiotics can be used if endophthalmitis is suspected.
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